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Essentials: Control Your Brain Chemistry for Focus, Motivation & Well-Being
6 Agustus 2026
In this Huberman Lab Essentials episode, I explain how key neuromodulators shape motivation, energy, focus and mood throughout the day. I also describe a toolkit of science-supported behavioral, nutritional and supplement-based strategies to increase baseline levels for each neuromodulator, which can be modified to support your specific health and performance goals.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
Eight Sleep: https://eightsleep.com/huberman
ROKA: https://roka.com/huberman
Timestamps
(00:00:00) Optimize Neurochemicals for Health
(00:00:27) Neuromodulator Levels & 3 Daily Phases
(00:05:07) Hormones Modulate Neuromodulators
(00:06:56) Sponsor: Eight Sleep
(00:08:13) Effects of Key Neuromodulators
(00:10:16) Increase Motivation & Dopamine, Tools: Morning Sunlight; Caffeine
(00:13:30) Dopamine Supplements: Mucuna Pruriens, L-Tyrosine, Phenethylamine (PEA)
(00:16:34) Increase Dopamine, Tool: Deliberate Cold Exposure
(00:19:18) Sponsor: AG1
(00:20:31) Increase Epinephrine (Adrenaline) & Energy, Tools: Exercise, Cyclic Hyperventilation
(00:24:56) Enhance Focus & Acetylcholine: Choline-Rich Foods, Nicotine
(00:27:11) Acetylcholine Supplements: Alpha-GPC, Huperzine
(00:28:05) Sponsor: ROKA
(00:29:21) Serotonin & Mood, Tools: Gratitude, Tryptophan-Rich Foods
(00:31:49) Serotonin Supplement: Myo-inositol
(00:32:26) Using the Neurochemical Toolkit for Your Goals
Disclaimer & Disclosures
Learn more about your ad choices. Visit megaphone.fm/adchoices
In this Huberman Lab Essentials episode, I explain how key neuromodulators shape motivation, energy, focus and mood throughout the day. I also describe a toolkit of science-supported behavioral, nutritional and supplement-based strategies to increase baseline levels for each neuromodulator, which can be modified to support your specific health and performance goals. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman Timestamps (00:00:00) Optimize Neurochemicals for Health (00:00:27) Neuromodulator Levels & 3 Daily Phases (00:05:07) Hormones Modulate Neuromodulators (00:06:56) Sponsor: Eight Sleep (00:08:13) Effects of Key Neuromodulators (00:10:16) Increase Motivation & Dopamine, Tools: Morning Sunlight; Caffeine (00:13:30) Dopamine Supplements: Mucuna Pruriens, L-Tyrosine, Phenethylamine (PEA) (00:16:34) Increase Dopamine, Tool: Deliberate Cold Exposure (00:19:18) Sponsor: AG1 (00:20:31) Increase Epinephrine (Adrenaline) & Energy, Tools: Exercise, Cyclic Hyperventilation (00:24:56) Enhance Focus & Acetylcholine: Choline-Rich Foods, Nicotine (00:27:11) Acetylcholine Supplements: Alpha-GPC, Huperzine (00:28:05) Sponsor: ROKA (00:29:21) Serotonin & Mood, Tools: Gratitude, Tryptophan-Rich Foods (00:31:49) Serotonin Supplement: Myo-inositol (00:32:26) Using the Neurochemical Toolkit for Your Goals Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
